Biochemistry of the Iris & Lens
Objectives: Upon completion of this conference the resident/student should be able to
- Describe the structure and chemical composition of iris, ciliary body and lens,
- Be aware of the physiology of iris, ciliary body and lens,
- Be aware of the unique features of the iris, ciliary body and the lens.
Assignment: Please read chapters 9 and 11 (in part IV, Biochemis
try and Metabolism) in Fundamentals and Principles of Ophthalmology, BCSC Section 2.
Recommended, but not required:
1. Davis-Silberman N, and Ashery-Padan R.2008. Iris development in vertebrates; genetic and molecular considerations. Brain Res. 4;1192:17-28.
2. Bloemendal H, de Jong W, Jaenicke R, Lubsen NH, Slingsby C, and Tardieu A. 2004. Ageing and vision: structure, stability and function of lens crystallins. Prog Biophys Mol Biol. 86(3):407-85.
Stem Cells in the Eye
Objectives: Upon completion of this conference the resident/student should be able to
- Describe the characteristics of adult stem cells, embryonic stem cells, induced pluripotent stem cells (iPS)
- Describe the corneal structure and the different stem cells for corneal epithelium, stroma and endothelium
- Describe the possible stem cell-based therapies for retinal diseases
Reading Assigment: Please look over last years slides (attached) and read the attached stem cell related journal articles
